The Challenge

Despite advances in genomic profiling, many cancer patients still experience treatment failure with first-line therapy. Genomic data alone cannot predict drug response with certainty, leaving oncologists to rely on population-based guidelines that may not reflect individual tumor biology.

The result: Trial and error approaches, delayed time to effective treatment, unnecessary toxicity, and higher healthcare costs.

The OncoForma Approach

OncoForma bridges the gap between genomic potential and functional reality by testing drugs directly on patient-derived organoids.

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Patient-Derived Organoids

We culture 3D organoids from patient tumor tissue that maintain the cellular architecture and genetic characteristics of the original tumor

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Comprehensive Drug Panel

Test against 1,800+ compounds including FDA-approved therapies, off-label options, and promising investigational agents

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Integrated Analysis

Functional drug response data combined with genomic profiling for comprehensive treatment guidance

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Rapid Turnaround

Clinician-ready report delivered in 4-6 weeks — fast enough to inform treatment decisions

Medical research and analysis

What's Included in the Report

  • Ranked list of most effective therapies based on functional testing
  • IC50 values and dose-response curves for tested compounds
  • Integration with genomic data (mutations, copy number alterations)
  • Identification of synergistic drug combinations
  • Resistance predictions based on observed patterns
  • Clinical interpretation and treatment recommendations
  • References to supporting clinical evidence and guidelines

Sample Requirements

  • Tissue type: Fresh tumor tissue or core biopsy
  • Minimum volume: 2-3mm³ viable tumor
  • Shipping: Cold pack (4°C), overnight delivery
  • Timeline: 4-6 weeks from sample receipt

Applicable Cancer Types

  • Colorectal cancer
  • Pancreatic cancer
  • Gastric/GI cancers
  • Ovarian cancer
  • Other solid tumors (contact us)

Join Our Early Pilot Program

We're currently enrolling patients for our validation study. Participating oncologists will receive:

Priority Access

Early access to testing for your patients

Reduced Fees

Pilot program pricing for initial cases

Collaboration

Opportunity to contribute to validation research

Support

Dedicated scientific liaison for case consultation

Request Information

Interested in OncoForma for your practice? Fill out the form below and we'll be in touch within 24 hours.

Frequently Asked Questions

How does this differ from genomic testing?

Genomic testing identifies mutations but cannot predict drug response with certainty. OncoForma tests drugs directly on living tumor cells to measure actual therapeutic effect, providing functional validation of treatment options.

What is the success rate for organoid culture?

Our success rate exceeds 85% for suitable tissue samples. We work closely with pathology teams to ensure optimal sample collection and handling.

Is this covered by insurance?

We are working with payers to establish reimbursement pathways. Currently, this is offered as a fee-for-service test. We can provide documentation to support patient reimbursement claims.

How do I order a test?

Contact us through the form above or email info@oncoforma.com. We'll provide sample collection kits, shipping instructions, and requisition forms.

Can you test drug combinations?

Yes. Our platform can identify synergistic combinations and test multi-drug regimens commonly used in clinical practice.